How was the Histotype Px® Colorectal marker developed?

Histotype Px® Colorectal* cancer marker is the most advanced deep convolutional neural network algorithm for determining prognosis in colorectal cancer based on standard histology images. The colorectal algorithm is robust and based on solid ground truth and extensive training and testing with in total 4500 patient samples, 90 million image tiles, from +200 sites in 8 countries. The slides were prepared at several sites, scanned at two sites with two different scanners, ensuring that the test can be used in clinical practice.

*The early version of Histotype Px® Colorectal was named DoMore-V1-CRC (and misc. variations of this description) during development in the DoMore! Project. The CE-IVD certified product Histotype Px® Colorectal is an updated version.